Please use this identifier to cite or link to this item: https://apo.ansto.gov.au/dspace/handle/10238/4861
Title: Unexpected low-temperature behaviour of piroxicam monohydrate
Authors: Fucke, K
Edwards, AJ
Probert, MR
Tallentire, SE
Howard, JAK
Steed, JW
Keywords: Neutron diffraction
Enthalpy
Crystals
Polycarbonates
Water
Drugs
Issue Date: 18-Mar-2013
Publisher: Wiley-VCH Verlag
Citation: Fucke, K., Edwards, A. J., Probert, M. R., Tallentire, S. E. Howard, J. A. K., & Steed, J. W. (2013). Unexpected low-temperature behaviour of piroxicam monohydrate. Chemical Physics and Physical Chemistry, 14 (4), 675-679. doi:10.1002/cphc.201200316
Abstract: Upon cooling the monohydrate of the anti-inflammatory drug piroxicam shows reversible splitting. The cell also shows an irregular contraction over temperature and has a memory effect of its thermal history. This is due to strongly hydrogen bonded chains present in the monohydrate, which allow the crystal domains to contract separately from each other. © 2013, Wiley-VCH Verlag.
Gov't Doc #: 5164
URI: http://dx.doi.org/10.1002/cphc.201200316
http://apo.ansto.gov.au/dspace/handle/10238/4861
ISSN: 1439-4235
Appears in Collections:Journal Articles

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