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https://apo.ansto.gov.au/dspace/handle/10238/4861| Title: | Unexpected low-temperature behaviour of piroxicam monohydrate |
| Authors: | Fucke, K Edwards, AJ Probert, MR Tallentire, SE Howard, JAK Steed, JW |
| Keywords: | Neutron diffraction Enthalpy Crystals Polycarbonates Water Drugs |
| Issue Date: | 18-Mar-2013 |
| Publisher: | Wiley-VCH Verlag |
| Citation: | Fucke, K., Edwards, A. J., Probert, M. R., Tallentire, S. E. Howard, J. A. K., & Steed, J. W. (2013). Unexpected low-temperature behaviour of piroxicam monohydrate. Chemical Physics and Physical Chemistry, 14 (4), 675-679. doi:10.1002/cphc.201200316 |
| Abstract: | Upon cooling the monohydrate of the anti-inflammatory drug piroxicam shows reversible splitting. The cell also shows an irregular contraction over temperature and has a memory effect of its thermal history. This is due to strongly hydrogen bonded chains present in the monohydrate, which allow the crystal domains to contract separately from each other. © 2013, Wiley-VCH Verlag. |
| Gov't Doc #: | 5164 |
| URI: | http://dx.doi.org/10.1002/cphc.201200316 http://apo.ansto.gov.au/dspace/handle/10238/4861 |
| ISSN: | 1439-4235 |
| Appears in Collections: | Journal Articles |
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